Sunday, June 13, 2010
One Gram Stain a day... keep the mystery away?
Histoplasmosis is fungal disease caused by Histoplasma capsulatum. Lungs are frequently affected, leading to acute pulmonary histoplasmosis. In human body at 37C, the organism is in yeast form. It is transmitted by inhalation of spores from soil. It looks like a pocketful of jewel inside the macrophage in the picture. Initially macrophages get infected and act as vehicles that takes the fungus around the body via blood, thereby spreading the infection. Cell-mediated immunity will eventually kick in and eradicate the organism, if the host immune system is well-maintained.
No puppy photos today... Good night!
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